Grandaxin (Tofisopam) 50mg CAS NO.22345-47-7

Contraindications:

Hypersensitivity to the active or any other component of the drug or any other benzodiazepines ;

state, accompanied by severe psychomotor agitation , aggression or severe depression ;

decompensated respiratory failure ;

I trimester of pregnancy;

lactation ;

syndrome, sleep apnea ( history);

simultaneous application of tacrolimus , sirolimus , cyclosporine ;

galactose intolerance , congenital lactase deficiency or malabsorption of glucose and galactose ( product contains lactose monohydrate) .

Precautions: decompensated chronic respiratory distress , acute respiratory failure in history, angle-closure glaucoma , epilepsy , organic brain lesions ( eg, atherosclerosis ) .

Pregnancy and breast-feeding:

Contraindicated in I trimester of pregnancy. At the time of treatment should stop breastfeeding.

Side effects:

GI : loss of appetite , constipation, increased separation of gas , nausea , dry mouth . In some cases, possible congestive jaundice .

CNS: may experience headache, insomnia, irritability , agitation , confusion, seizures may occur in patients with epilepsy .

Allergic reactions: rash, scarlatiniform rash, itching.

On the part of the musculoskeletal system : muscle tension, muscle pain.

The respiratory system : respiratory depression .

 

Contraindications:

Hypersensitivity to the active or any other component of the drug or any other benzodiazepines ;

state, accompanied by severe psychomotor agitation , aggression or severe depression ;

decompensated respiratory failure ;

I trimester of pregnancy;

lactation ;

syndrome, sleep apnea ( history);

simultaneous application of tacrolimus , sirolimus , cyclosporine ;

galactose intolerance , congenital lactase deficiency or malabsorption of glucose and galactose ( product contains lactose monohydrate) .

Precautions: decompensated chronic respiratory distress , acute respiratory failure in history, angle-closure glaucoma , epilepsy , organic brain lesions ( eg, atherosclerosis ) .

Pregnancy and breast-feeding:

Contraindicated in I trimester of pregnancy. At the time of treatment should stop breastfeeding.

Side effects:

GI : loss of appetite , constipation, increased separation of gas , nausea , dry mouth . In some cases, possible congestive jaundice .

CNS: may experience headache, insomnia, irritability , agitation , confusion, seizures may occur in patients with epilepsy .

Allergic reactions: rash, scarlatiniform rash, itching.

On the part of the musculoskeletal system : muscle tension, muscle pain.

The respiratory system : respiratory depression .

 

Dosage and administration:

The dosage set individually according to the patient, the clinical form of the disease and individual sensitivity to the drug. Adults appoint 50-100 mg (1-2 tabs). 1-3 times a day. Of irregular use can take 1-2 tablets. The maximum daily dose - 300 mg.

Elderly patients and patients with renal insufficiency: the daily dose is reduced approximately 2-fold.